Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
| Phenotype | Phenotype.cls#treated_versus_cont_repos |
| Upregulated in class | treated |
| GeneSet | REACTOME|REACT_11052.2 |
| Enrichment Score (ES) | 0.823368 |
| Normalized Enrichment Score (NES) | 1.6842573 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.016670547 |
| FWER p-Value | 0.349 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 6635 | SNRPE (small nuclear ribonucleoprotein polypeptide E) | 43 | 207.433 | 0.1121 | Yes | ||
| 2 | 6636 | SNRPF (small nuclear ribonucleoprotein polypeptide F) | 93 | 154.388 | 0.1947 | Yes | ||
| 3 | 25929 | GEMIN5 (gem (nuclear organelle) associated protein 5) | 175 | 109.063 | 0.2507 | Yes | ||
| 4 | 6634 | SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide 18kDa) | 196 | 103.434 | 0.3067 | Yes | ||
| 5 | 57122 | NUP107 (nucleoporin 107kDa) | 276 | 89.588 | 0.3521 | Yes | ||
| 6 | 8480 | RAE1 (RAE1 RNA export 1 homolog (S. pombe)) | 322 | 83.312 | 0.3958 | Yes | ||
| 7 | 6632 | SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide 16kDa) | 352 | 78.903 | 0.4378 | Yes | ||
| 8 | 10419 | PRMT5 (protein arginine methyltransferase 5) | 413 | 71.043 | 0.4740 | Yes | ||
| 9 | 129401 | NUP35 (nucleoporin 35kDa) | 502 | 61.873 | 0.5037 | Yes | ||
| 10 | 6633 | SNRPD2 (small nuclear ribonucleoprotein D2 polypeptide 16.5kDa) | 528 | 60.471 | 0.5358 | Yes | ||
| 11 | 6628 | SNRPB (small nuclear ribonucleoprotein polypeptides B and B1) | 697 | 49.717 | 0.5548 | Yes | ||
| 12 | 79023 | NUP37 (nucleoporin 37kDa) | 770 | 46.189 | 0.5767 | Yes | ||
| 13 | 4686 | "NCBP1 (nuclear cap binding protein subunit 1, 80kDa)" | 860 | 42.266 | 0.5956 | Yes | ||
| 14 | 9972 | NUP153 (nucleoporin 153kDa) | 924 | 39.672 | 0.6144 | Yes | ||
| 15 | 79084 | WDR77 (WD repeat domain 77) | 950 | 38.449 | 0.6343 | Yes | ||
| 16 | 79833 | GEMIN6 (gem (nuclear organelle) associated protein 6) | 967 | 37.974 | 0.6544 | Yes | ||
| 17 | 23636 | NUP62 (nucleoporin 62kDa) | 980 | 37.692 | 0.6746 | Yes | ||
| 18 | 22916 | "NCBP2 (nuclear cap binding protein subunit 2, 20kDa)" | 986 | 37.528 | 0.6950 | Yes | ||
| 19 | 10762 | NUP50 (nucleoporin 50kDa) | 1132 | 32.860 | 0.7059 | Yes | ||
| 20 | 23165 | NUP205 (nucleoporin 205kDa) | 1143 | 32.605 | 0.7234 | Yes | ||
| 21 | 4927 | NUP88 (nucleoporin 88kDa) | 1149 | 32.455 | 0.7410 | Yes | ||
| 22 | 1207 | "CLNS1A (chloride channel, nucleotide-sensitive, 1A)" | 1186 | 31.453 | 0.7566 | Yes | ||
| 23 | 6606 | "SMN1 (survival of motor neuron 1, telomeric)" | 1233 | 30.350 | 0.7710 | Yes | ||
| 24 | 11218 | DDX20 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 20) | 1420 | 26.719 | 0.7765 | Yes | ||
| 25 | 50628 | GEMIN4 (gem (nuclear organelle) associated protein 4) | 1589 | 24.086 | 0.7815 | Yes | ||
| 26 | 53371 | NUP54 (nucleoporin 54kDa) | 1604 | 23.859 | 0.7940 | Yes | ||
| 27 | 9631 | NUP155 (nucleoporin 155kDa) | 1641 | 23.360 | 0.8051 | Yes | ||
| 28 | 51808 | "RNUXA (RNA U, small nuclear RNA export adaptor (phosphorylation regulated))" | 1660 | 23.100 | 0.8169 | Yes | ||
| 29 | 23279 | NUP160 (nucleoporin 160kDa) | 1804 | 20.988 | 0.8214 | Yes | ||
| 30 | 79760 | GEMIN7 (gem (nuclear organelle) associated protein 7) | 2057 | 18.256 | 0.8190 | Yes | ||
| 31 | 5903 | RANBP2 (RAN binding protein 2) | 2164 | 17.399 | 0.8234 | Yes | ||
| 32 | 23511 | NUP188 (nucleoporin 188kDa) | 2623 | 13.256 | 0.8081 | No | ||
| 33 | 9688 | NUP93 (nucleoporin 93kDa) | 2709 | 12.814 | 0.8109 | No | ||
| 34 | 55746 | NUP133 (nucleoporin 133kDa) | 2787 | 12.281 | 0.8139 | No | ||
| 35 | 79902 | NUP85 (nucleoporin 85kDa) | 3289 | 9.586 | 0.7945 | No | ||
| 36 | 348995 | NUP43 (nucleoporin 43kDa) | 3355 | 9.350 | 0.7964 | No | ||
| 37 | 96764 | TGS1 (trimethylguanosine synthase homolog (S. cerevisiae)) | 3388 | 9.200 | 0.7999 | No | ||
| 38 | 23225 | NUP210 (nucleoporin 210kDa) | 3396 | 9.169 | 0.8046 | No | ||
| 39 | 8487 | SIP1 (survival of motor neuron protein interacting protein 1) | 4233 | 6.009 | 0.7667 | No | ||
| 40 | 9883 | POM121 (POM121 membrane glycoprotein (rat)) | 5027 | 3.978 | 0.7298 | No | ||
| 41 | 8021 | NUP214 (nucleoporin 214kDa) | 16014 | -2.513 | 0.1895 | No | ||
| 42 | 10073 | SNUPN (snurportin 1) | 16960 | -4.145 | 0.1451 | No | ||
| 43 | 8086 | "AAAS (achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A))" | 16985 | -4.211 | 0.1463 | No | ||
| 44 | 7175 | TPR (translocated promoter region (to activated MET oncogene)) | 17416 | -5.336 | 0.1280 | No | ||
| 45 | 11097 | NUPL2 (nucleoporin like 2) | 18164 | -8.850 | 0.0961 | No | ||
| 46 | 6637 | SNRPG (small nuclear ribonucleoprotein polypeptide G) | 19107 | -18.986 | 0.0601 | No |
